Source: Txawv Tebchaws Tsiaj Cov Txiv Khaub Ncaws, Ua Npua thiab Nqaij Qaib, No.01,2019

Abstract: Daim ntawv no qhia cov ntawv thov ntawmCov tshuaj tua kab mob hauv cov nqaij qaib ntau lawm, thiab nws cov cawv ntawm nqaij qaib ntau lawm, cov tshuaj tiv thaiv kab mob, tshuaj tiv thaiv cov tshuaj tsis zoo thiab tshuaj noj ua yeeb yam ntawm cov tshuaj tua kab mob hauv kev lag luam nqaij qaib.

Cov lus tseem ceeb: tshuaj tua kab mob; Nqaij qaib; kev ua ntau lawm; Kev tiv thaiv kab mob tsis muaj zog; Cov tshuaj tsis txaus; Tshuaj Kuj

Daim Duab Nruab Nrab Tsis Muaj .: S831 Daim Ntawv Logo Code: C Xov Xwm Tsis yog.: 1001-0769 (2019) 01-0056-03

Cov tshuaj tua kab mob lossis cov tshuaj tua kab mob tuaj yeem cuam tshuam thiab cov ntawv qhia zoo sib xws nyob rau hauv qee qhov kev pom zoo ntawm cov tshuaj tua kab mob ntawm cov nqaij qaib pib hauv Suav teb. Tam sim no, ntau tshaj 20 cov tshuaj tua kab mob tau siv dav, kev tiv thaiv kev txhawb nqa nqaij qaib ntau lawm, kev tshawb fawb txog cov tshuaj tua kab mob ntawm cov qaib yog qhia raws li cov hauv qab no.

1; Cov nyhuv ntawm cov tshuaj tua kab mob ntawm nqaij qaib ntau lawm

Daj, DynamyCy, Bacidin Zinc, AmamyCy, tuaj yeem siv los txhawb kev loj hlob, cuam tshuam los sis tua cov kab mob plab hnyuv tus kab mob hnyuv sab nrauv; txo qhov muaj kev phom sij; Ua tsiaj txoj hnyuv nyias nyias nyias, txhim kho txoj hnyuv mucosa permeability, nrawm dua qhov nqus ntawm cov as-ham; Inhibit txoj hnyuv microbial thiab kev ua haujlwm, txo cov microbial noj ntawm cov as-ham thiab lub zog, thiab nce cov khoom noj muaj txiaj ntsig hauv cov qaib; Inhibit cov kab mob hnyav ua phem tsim cov roj hmab metabolites [2]. Tseem ceeb nce qhov nruab nrab txhua hnub nyhav ntawm 11 mus rau 20 hnub qub broilers thiab nruab nrab txhua hnub pub rau 5 txog 41 hnub ua kua txiv; Ntxiv FlavamyCin (5 mg / kg) nce qhov nruab nrab txhua hnub poob ntawm 22 txog 41-hnub qub brooilers.ni jiang li al. ntxiv 4 mg / kg likromycin thiab 50 mg / kg zinc; thiab 20 mg / kg colistin rau 26 d, uas nce ntxiv qhov hnyav txhua hnub [5] .wang Manhong li al. Ntxiv enlamycin, Bacracin Zinc thiab Naceptide rau 42, D feem ntau hauv 1-hnub AA qhov hnyav loj zuj zus thiab pub nqaij tawm zuj zus los ntawm [6].

2; Qhov cuam tshuam ntawm cov tshuaj tua kab mob ntawm kev tiv thaiv kab mob hauv cov qaib

Lub cev tiv thaiv kab mob ntawm cov tsiaj txhu thiab nqaij qaib ua rau muaj kab mob kis tau, txo lawv txoj kev loj hlob. epithelium thiab plab hnyuv Lymphoid nqaij, yog li txo lub xeev ua kom muaj zog tiv thaiv lub cev; cuam ​​tshuam nrog immunoglemulin synthesis; txo cov phagocytosis tsawg; thiab txo cov kev ua ub no ntawm lub cev ntawm lub cev lymphocytes [7] .jin Jiushan li al. ntxiv 0.06%, 0.010% thiab 0.15% ntawm chloramphenicol rau 2 txog kev ua npaws thiab tsis muaj zog ntawm cov nqaij qaib thiab cov pob txha tseem ceeb. GoldomCin, thiab qhov hnyav ntawm thymus, thiab bursa tau txo qis [9] ntawm 42 hnub ntawm Airm.Guo Xinhua li al. ntxiv 150 mg / kg ntawm gilomycin nyob rau hauv pub ntawm 1-hnub-laus instarit tsis zoo li t lymphocytes thiab b lymphocytes thiab b lymphocytes thiab b lymphocytes thiab b lymphocytes thiab b lymphocytes thiab b lymphocytes thiab b Fed 4 MG / kg Lincomycin Hydrocomalide, 50 mg thiab 20 mg / kg broders feem, thiab cov thnymus index tsis tau hloov pauv ntau. Lub zais ntawm iGA hauv txhua ntu ntawm peb pawg neeg tau poob qis, thiab tus nqi ntawm cov kabmob igm nyob rau hauv cov kab mob Dincin Dincin txo qis dua [5]. Ntxiv 50 mg / kg ntawm gilomycin rau 1-hnub-laus cov txiv neej noj tshuaj ntsuab, thiab yog li txhawb nqa kev tiv thaiv kab mob [11], tawm tsam lwm txoj kev tshawb fawb.

3; Cov nyhuv ntawm cov tshuaj tua kab mob ntawm nqaij qaib hnyuv muaj

Muaj ntau cov kab mob sib kis hauv cov hnyuv ntawm cov kab mob uas muaj kev cuam tshuam nrog cov kab mob uas muaj kev sib cuam tshuam ntawm cov kab mob uas muaj kev sib cuam tshuam, uas tau txo qis kev sib cuam tshuam, uas tau txo qis kev sib cuam tshuam ntawm cov kab mob uas muaj kev sib raug zoo, uas muaj txiaj ntsig zoo rau cov kab mob no, Cov tshuaj tua kab mob tuaj yeem cuam tshuam thiab tua txhua cov kab mob me me hauv cov qaib, uas tuaj yeem ua rau cov kab mob zom thiab ua rau cov hnyuv rog. ntxiv 100 mg / kg gilomycin rau cov khoom noj yooj yim ntawm 1 hnub yog tsis muaj qhov sib txawv ntawm cov pab pawg ntawm pawg, tsis muaj qhov sib txawv ntawm ob tus kab mob tom qab hnub nyoog 14 hnub; Tus naj npawb ntawm Escherichia Coli tau tsawg dua li pawg tswj hwm ntawm 7,14,21 thiab [12] nrog cov tshuaj tiv thaiv Lactobacillus tau ua tiav [13]. Pub 1-hnub pob kws npuas dej noj mov ntxiv nrog 50 mg, cov menyuam qaib thiab ua rau muaj cov kab mob AERACH) AA cov zaub mov qaib, uas txo cov polymorphism ntawm txoj hnyuv muaj zog [15] Rectum.Lei Xinjian ntxiv 200 mg / kg ;;;;;;;; Bacterereracin zinc thiab 30 mg / kg VirginiaMycin feem ntau txo tus kab mob ceci thiab Lactobacillus nyob rau hauv Cecum, tab sis kev nplua nuj ntawm Cecum cov kab mob kuj Txo [18] .Tus tseem muaj ob peb tug ntxiv qhia tias qhov sib ntxiv ntawm 20 mg / kg sulfate antientemium bife [19] nyob rau hauv cov txheej txheem cecal ntawm 21-hnub-laus broilers.

4; Muaj txiaj ntsig ntawm cov tshuaj tua kab mob ntawm cov khoom lag luam qaib

Nqaij qaib thiab qe zoo yog ze rau cov zaub mov muaj txiaj ntsig, thiab nce cov ntsiab lus ntawm cov nqaij uas tsis muaj txiaj ntsig thiab ua kom cov tshuaj ntsuab uas muaj feem xyuam rau cov tshuaj tua kab mob tshiab thiab ua kom cov tshuaj tiv thaiv kab mob uas muaj Ib me ntsis tsis zoo rau cov khoom siv lub cev ntawm cov nqaij ua tau zoo thiab cov nqaij qaib ua kom zoo li cov nqaij qaib hauv siab. tus nqi nce los ntawm 0.28%, 2.72%, 8.76%, thiab cov nqaij pectoral sib zog nce los ntawm [22] .yang minxin fed 45 mg / kg ntawm gilomycin rau 1-hnub-laus kev kawm txog ntawm AFE lub sijhawm pub mis thiab T-SKATIONS Tab sis qhov rhiab thiab saj tau zoo dua thiab cov qhab nia kev txheeb xyuas cov qhab nia zoo dua [24] .liu wenlong li al. Pom tias tag nrho cov nyiaj ntawm cov khoom sib co, aldehydes, cov dej cawv thiab cov khoom siv qe me me tau nce siab dua li cov qaib cov qaib. Kev yug me nyuam yam tsis muaj tshuaj tua kab mob tuaj yeem txhim kho cov ntsiab lus tsw ntxiv ntawm [25] hauv cov qe ntau dua tshuaj tua kab mob.

5; Muaj txiaj ntsig ntawm cov tshuaj tua kab mob ntawm cov khoom seem hauv cov khoom lag luam qaib

Nyob rau hauv xyoo tsis ntev los no, qee cov khoom lag luam nrhiav cov tshuaj tiv thaiv kab mob hauv cov qaib thiab cov qe thiab cov qe thiab cov qe thiab cov qe thiab cov qe tau pom, yog 4.66 mg / kg and porg Qhov siab tshaj plaws ntawm streptomycin hauv qe yog 0.7 mg / kg thiab tus nqi nrhiav tau 20% [26] .wang chunlin li al. Pub cov khoom noj muaj zog ntxiv nrog 50 mg / kg ntawm gilmomycin rau 1-hnub qaib laus. Nqaij qaib muaj Gilomycin seem nyob hauv daim siab thiab raum, nrog qhov siab tshaj ntawm Gilmycin hauv cov leeg nqaij muaj tsawg dua 0.10 g / g (siab tshaj plaws rau kev txwv); thiab cov seem hauv daim siab thiab lub raum yog 23 diam ;;;;;;;;;;; yog qis dua qhov kev sib raug zoo kawg ntawm kev txwv [28] Tom qab 28] Tom qab 283 piece ntawm cov tsiaj txhu muaj sib npaug nrog 21,5]. Qe cov qauv, thiab pom tias TetRacyCline thiab Doxycycline tau rov qab [30] hauv cov qe ua piv txwv.Chen Lin li al. qhia tau tias nrog kev ncua ntawm cov tshuaj tiv thaiv tshuaj, kev sib txuam ntawm cov tshuaj tua kab mob hauv siab, thiab ntau dua [31] nyob rau hauv resistant qe.ciu jinli li al. tau 250 mg / u rau brooilers ntawm hnub sib txawv ;; thiab 333 mg / l ntawm 50% hydrochloride soluble hmoov ib hnub rau ib hnub rau daim siab thiab cov leeg qis dua [32] tom qab 5 d rho tawm.

6; Cov nyhuv ntawm cov tshuaj tua kab mob ntawm cov tshuaj tiv thaiv hauv cov nqaij qaib

Long-term excessive use of antibiotics in livestock and poultry will produce multiple drug-resistant bacteria, so that the whole pathogenic microbial flora will gradually change to the direction of drug resistance to [33].In recent years, the emergence of drug resistance in chicken-derived bacteria is becoming more and more serious, the drug-resistant strains are increasing, the drug resistance spectrum is becoming more and more wide, and the rhiab rau tshuaj tua kab mob yog txo qis, uas coj teeb meem rau cov kev tiv thaiv kabmob thiab tswj.liu jinhua li al. 116 S. Aureus sib cais cais los ntawm qee cov nqaij qaib ua liaj ua teb hauv cov yeeb tshuaj tiv thaiv, feem ntau yog cov tshuaj tiv thaiv ntau ntxiv, thiab siv tshuaj tiv thaiv ntau xyoo nyob rau xyoo [34] .zhang Xiuying li al. 25 salmonella strains los ntawm qee cov nqaij qaib ua liaj ua teb, cov kab mob streptomycin, thiab, Yuan lin li al. Pom tias 30 E. coli plhuav cais nyob rau hauv Harbin muaj ntau cov tshuaj tiv thaiv, amomicillin yog 100%, thiab cipycin thiab cipycin thiab polymyxin b.wang b.wang b.wang mewen li al. cais 10 hom kab mob streptococcus los ntawm cov kab mob uas tuag taus, thiab cov tshuaj pleev ib ce, thiab tshuaj pleev ib yam, thiab cov tshuaj pleev roj ntsa iab, thiab cov neeg ua haujlwm siab tawv ntawm tsis kam mus rau quinolones, cepharosporins, tetracyclines yog cov kab mob sib xyaw ua ke, menicillined yog qhov tsis muaj txiaj ntsig, avilomypyridine, halilomycin, halilomycin thiab ua kom tiav [39].

Kom suav tau, kev siv tshuaj tua kab mob hauv cov nqaij qaib kev lag luam thiab cov tshuaj tiv thaiv kev nyab xeeb, tsis muaj kev phom sij rau cov nqaij thiab cov nqaij qaib, cuam tshuam nrog kev tiv thaiv kab mob rau cov nqaij thiab cov nqaij qaib, puas yog cov nqaij qaib cov tshuaj tiv thaiv kab mob thiab cov nqaij qaib ua ke Nyob rau hauv 2006, European Under Cov tshuaj tua kab mob hauv cov tsiaj txhu thiab kev txhim kho hauv ntiaj teb no txhawm rau tiv thaiv kev tiv thaiv kabmob, thiab txhawb nqa kev txhim kho kev tiv thaiv kab mob, thiab txhawb nqa kev txhim kho lub ntiaj teb los tiv thaiv kev tiv thaiv, uas tseem yuav ua Txoj kev qhia kev txhim kho ntawm kev lag luam nqaij qaib yav tom ntej.

References: (39 tsab xov xwm, raug rho tawm)