Imidacloprid thiab Moxidectin Spot-on Solutions (rau miv)

【Cov khoom xyaw】

Imidacloprid, Moxidectin

【Qhov tshwm sim】

Yellow to brown yellow kua.

Pharmacological kev txiav txim:Antiparasitic tshuaj. Pharmacodynamics: Imidacloprid yog ib tiam tshiab ntawm chlorinated nicotine insecticides. Nws muaj affinity siab rau postsynaptic nicotinic acetylcholine receptors nyob rau hauv lub hauv paus paj hlwb kab ntawm kab, thiab muaj peev xwm inhibit qhov kev ua ntawm acetylcholine, ua rau parasite tuag tes tuag taw. Nws muaj txiaj ntsig zoo rau cov neeg laus fleas thiab cov tub ntxhais hluas fleas ntawm ntau theem, thiab tseem muaj kev tua cov dev mub hauv ib puag ncig.

Cov txheej txheem ntawm kev ua ntawm moxidectin zoo ib yam li abamectin thiab ivermectin, thiab nws muaj kev tua zoo rau cov kab mob sab hauv thiab sab nraud, tshwj xeeb tshaj yog nematodes thiab arthropods. Kev tso tawm ntawm butyric acid (GABA) nce nws txoj hlua khi rau postsynaptic receptor, thiab chloride channel qhib. Moxidectin kuj muaj kev xaiv thiab kev sib raug zoo siab rau glutamate mediated chloride ion channels, yog li cuam tshuam nrog neuromuscular teeb liab kis tau tus mob, so thiab tuag tes tuag taw cov kab mob, ua rau cov kab mob tuag taus.

Inhibitory interneurons thiab excitatory lub cev muaj zog neurons hauv nematodes yog nws qhov chaw ntawm kev ua, thaum nyob rau hauv arthropods nws yog lub neuromuscular hlws ris. Kev sib xyaw ntawm ob qho tib si muaj kev sib koom ua ke. Pharmacokinet ics: Tom qab thawj zaug kev tswj hwm, imidacloprid tau xa tawm sai sai rau cov miv lub cev saum npoo ntawm tib hnub, thiab tseem nyob ntawm lub cev ntawm lub sijhawm ua haujlwm 1-2 hnub tom qab kev tswj hwm, cov ntshav plasma concentration ntawm moxidectin hauv miv nce mus txog qib siab tshaj plaws. , thiab nws raug faib thoob plaws hauv lub cev hauv ib hlis thiab maj mam metabolized thiab tawm.

【Siv thiab ntau npaum】

Cov khoom no yog qhia rau kev tiv thaiv thiab kev kho mob ntawmhauv vivothiabhauv vitro kab mob parasitic nyob rau hauv miv. Cov khoom no yog qhia rau kev tiv thaiv thiab kev kho mob ntawm cov kab mob flea(Ctenocephalus felis), kho pob ntseg kab mob(Pruritus aris), kev kho mob ntawm plab hnyuv nematode (cov neeg laus, cov neeg laus tsis paub tab thiab L4 theem larvae ntawmToxocarria felisthiabHamnostoma tubuloides), tiv thaiv kab mob plawv (L3 thiab L4 theem juveniles heartworms). Thiab tuaj yeem pab kho kev ua xua dermatitis tshwm sim los ntawm fleas.

【Siv thiab ntau npaum】

Kev siv sab nraud. Ib koob tshuaj, miv ib 1kg lub cev qhov hnyav, 10mg imidacloprid 1mg moxidectin, sib npaug rau 0.1ml ntawm cov khoom no. Thaum prophylaxis los yog kev kho mob, nws raug nquahu kom noj ib hlis ib zaug. Txhawm rau tiv thaiv licking, tsuas yog siv rau ntawm daim tawv nqaij tom qab ntawm tus miv lub taub hau thiab caj dab.

【Side Effect】

(1) Hauv ib tus neeg mob, cov khoom no yuav ua rau muaj kev tsis haum tshuaj hauv zos, ua rau khaus ib ntus, cov plaub hau adhe sion, erythema lossis ntuav.Cov tsos mob no ploj mus yam tsis muaj kev kho mob.

(2) Tom qab kev tswj hwm, yog tias tus tsiaj licks qhov chaw tswj hwm, cov tsos mob ntawm lub paj hlwb tuaj yeem tshwm sim qee zaus, xws li kev zoo siab, tshee, cov tsos mob ntawm qhov muag (cov menyuam kawm ntawv dilated, pupillary reflexes, thiab nystagmus), ua pa txawv txav, salivation, thiab cov tsos mob xws li ntuav. ; Qee zaus hloov pauv tus cwj pwm xws li kev tsis txaus siab rau kev tawm dag zog, kev zoo siab, thiab tsis qab los noj mov.

【Cov kev ceev faj】

(1) Tsis txhob siv rau cov menyuam yaus hnub nyoog qis dua 9 lub lis piam. Tsis txhob siv rau cov miv uas ua xua rau cov khoom no. Cov dev cev xeeb tub thiab lactating dev yuav tsum ua raws li kws kho tsiaj cov lus qhia ua ntej siv.

(2) Cov miv hauv qab 1kg yuav tsum ua raws li kws kho tsiaj cov lus qhia thaum siv cov khoom no.

(3) Nws yog ib qho tsim nyog los tiv thaiv Collies, Old English Sheepdogs thiab lwm yam tsiaj los ntawm licking cov khoom no los ntawm lub qhov ncauj.

(4) Cov miv mob thiab miv nrog lub cev tsis muaj zog yuav tsum ua raws li cov kws kho tsiaj cov lus qhia thaum siv nws.

(5) Cov khoom no yuav tsum tsis txhob siv rau cov dev.

(6) Thaum lub sij hawm siv cov khoom no, tsis txhob cia cov tshuaj nyob rau hauv lub raj tshuaj tiv thaiv lub qhov muag thiab lub qhov ncauj ntawm lub qhov muag thiab lub qhov ncauj ntawm cov tsiaj los yog lwm yam tsiaj. Tiv thaiv cov tsiaj uas tau khiav tawm ntawm cov tshuaj los ntawm licking ib leeg. Tsis txhob kov lossis txiav cov plaub hau kom txog thaum cov tshuaj qhuav.

(7) Qee zaus 1 lossis 2 raug miv rau dej thaum lub sijhawm tswj hwm yuav tsis cuam tshuam rau kev ua tau zoo ntawm cov tshuaj. Txawm li cas los xij, cov miv nquag da dej nrog tshuaj zawv plaub hau los yog soaked hauv dej yuav cuam tshuam rau kev ua tau zoo ntawm cov tshuaj.

(8) Khaws cov me nyuam tsis txhob tiv tauj nrog cov khoom no.

(9) Tsis txhob khaws cia siab tshaj 30 ℃, thiab tsis txhob siv dhau hnub tas sij hawm ntawm daim ntawv lo.

(10) Cov neeg uas ua xua rau cov khoom no yuav tsum tsis txhob noj nws.

(11) Thaum muab tshuaj, tus neeg siv yuav tsum tsis txhob sib cuag nrog daim tawv nqaij, qhov muag thiab qhov ncauj ntawm cov khoom no, thiab tsis txhob noj, haus dej haus los yog haus luam yeeb; tom qab kev tswj hwm, tes yuav tsum tau ntxuav. Yog nws

yuam kev txaws ntawm daim tawv nqaij, ntxuav nws nrog xab npum thiab dej tam sim ntawd; yog hais tias nws yuam kev tawg rau hauv lub qhov muag, yaug nrog dej tam sim ntawd. Yog tias cov tsos mob tsis zoo, thov nrog kws kho mob tham

cov lus qhia.

(12) Tam sim no, tsis muaj cov tshuaj cawm siav rau cov khoom no; yog tias nqos los ntawm qhov yuam kev, lub qhov ncauj siv hluav taws xob tuaj yeem pab tshem tawm cov co toxins.

(13) Cov kuab tshuaj nyob rau hauv cov khoom no yuav paug cov ntaub ntawv xws li tawv, ntaub, yas, thiab pleev xim rau. Ua ntej qhov chaw tswj hwm qhuav, tiv thaiv cov ntaub ntawv no los ntawm kev tiv tauj lub chaw tswj hwm.

(14) Tsis txhob cia cov khoom no nkag mus rau hauv dej.

(15) Cov tshuaj tsis siv thiab cov khoom ntim yuav tsum muab pov tseg kom tsis muaj mob raws li cov cai hauv zos.

【Lub sijhawm rho nyiaj】Tsis muaj.

【Specifications】

(1) 0.4ml: Imidacloprid 40mg + Moxidectin 4mg

(2) 0.8ml: Imidacloprid 80mg + Moxidectin 8mg

【Storage】Muab kaw, khaws cia ntawm chav tsev kub.

【Lub neej txee】3 xyoo.