Cov khoom tseem ceeb: Doxycline hydroporide

Khoom: Cov khoom no yog lub teeb ntsuab.

Pharmacological txiav txim:

Pharmacyamics:Cov khoom no yog tetracycline broadum broadum caterpiotic nrog dav-spectrum cov nyhuv antibacterious. Cov kab mob rhiab muaj xws li cov kab mob grameriaph xws li pneumchellacter, condino, salmella, brolonthilus, klibebacter. Nws tseem tuaj yeem txwv rickettsia, mypsplasma thiab spelieta rau qee yam.

Pharmaconinetics:Sai kev yuav tsuaj, me ntsis cuam tshuam los ntawm khoom noj, siab bioavailability. Cov ntshav kom zoo yog kev tu kom ntev, cov ntaub so ntswg permeability muaj zog, kev faib tawm dav dav, thiab nws yooj yim kom nkag mus rau hauv tes. Lub suab nrov-lub sijhawm pom meej ntim ntawm kev faib tawm hauv cov dev yog li 1.5L / kg. Cov protein ntau khi rau cov dev 75% rau 86%. Ib nrab tsis ua los ntawm chelation nyob rau hauv txoj hnyuv, 75% ntawm tus aub cov koob tshuaj yog tshem tawm txoj kev no. Lub raum zoo zuj zus tsuas yog li 25%, biliary excretion yog tsawg dua 5%. Ib nrab-lub neej ntawm tus dev yog li 10 txog 12 teev.

Kev sib cuam tshuam yeeb tshuaj:

(1) Thaum noj nrog sodium bicarbonate, nws tuaj yeem nce tus peep hauv lub plab thiab txo cov kev nqus thiab kev ua ntawm cov khoom no.

(2) Cov khoom no tuaj yeem tsim cov ntau yam nrog cov calcium, thiab lwm yam tshuaj pleev ib ce, yog li thaum lawv ua haujlwm txo, ua rau cov tshuaj tiv thaiv ntshav ntxiv.

(3) Kev siv tib yam nrog cov diuretics muaj zog xws li furthiamide tuaj yeem siv tsis taus kev puas tsuaj rau lub plab zom mov.

(4) tuaj yeem cuam tshuam nrog cov kab mob bactericidal ntawm penicillin ntawm cov kab mob yug me nyuam, yuav tsum zam kev siv tib yam.

Qhia Qhia:

Kev kis tus kab mob zoo, cov kab mob tsis zoo thiab mypsplasma. Kev mob ntsws (myCoplasma Dermatosis, kev sib tw giritinginingination, kev mob plab zom mov, thiab lwm yam.

Kev siv thiab ntau npaum li cas:

Doxycycline. Rau sab hauv kev tswjfwm: ib koob tshuaj, 5 ~ 10mg rau ib 1kg lub cev rau dev thiab miv. Nws yog siv ib zaug ib hnub rau 3-5 hnub. Los yog raws li kws kho mob tau sau tseg. Nws raug nquahu kom coj tom qab pub mis thiab haus dej ntau dua tom qab kev tswj hwm qhov ncauj.

Ceeb Toom:

(1) Nws tsis pom zoo rau cov dev thiab miv tsawg dua peb lub lis piam ua ntej xa khoom, lactation, thiab 1 lub hnub nyoog.

(2) Siv nrog kev ceev faj hauv dev thiab miv nrog mob siab loj thiab raum tsis sib xws.

(3) Yog tias koj yuav tsum khaws cov tshuaj calcium, cov tshuaj tiv thaiv hlau, tshuaj tiv thaiv, sodium bicarbonate, thiab lwm lub sijhawm, thov tsawg kawg 2H ntu.

(4) Nws raug txwv siv nrog diuretics thiab penicillin.

(5) Ua ke nrog phenobarbital thiab anticoagulant yuav cuam tshuam kev ua si ntawm ib leeg.

Cov kev tsis zoo:

(1) hauv cov dev thiab miv, feem ntau cov kev tsis zoo ntawm qhov ncauj tau ntuav, raws plab, thiab tsis qab los noj mov. Txhawm rau txo cov kev cai txo qis, tsis muaj qhov txo qis hauv kev nqus tshuaj tau pom thaum noj nrog zaub mov.

(2)40% of treated dogs had an increase in liver function-related enzymes (alanine aminotransferase, basic conglutinase). Qhov chaw kho mob tseem ceeb ntawm lub siab ua haujlwm ntsig txog enzymes tsis meej.

(3) Qhov ncauj doxycycline tuaj yeem ua rau esophageal stenosis hauv miv, xws li cov ntsiav tshuaj ntawm qhov ncauj, yuav tsum tau coj nrog tsawg kawg 6ml dej, tsis qhuav.

(4) Kev Kho Mob nrog TetRacycline (tshwj xeeb tshaj yog lub sijhawm ntev) tuaj yeem ua rau cov kab mob uas tsis muaj kab mob fungi (ob zaug kis).

Hom Phiaj: Tsuas yog rau miv thiab dev.

Cov Lus Qhia Tshwj Xeeb: 200Mg / ntsiav tshuaj / ntsiav tshuaj